A transition from the use of HFA 134a and HFA 227 as propellants in metered dose inhalers (MDIs) to lower global warming potential (LGWP) propellants is in the early stages
Learn more about these LGWP propellants:
Learn more about regulations affecting LGWP propellants:
Learn more about the transition:
View IPAC-RS’s October 11, 2023 Workshop on the Transition to Low Global Warming Potential Propellants for Metered Dose Inhalers
Recent news about LGWP propellants:
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Lupin announces plans to develop MDIs using Honeywell’s Solstice Air HFO-1234ze
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UK MHRA approves AstraZeneca’s reformulated Trixeo (Breztri) Aerosphere MDI with HFO-1234ze as the propellant
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Chiesi announces plans for LGWP MDI production facility
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Bespak and OzUK extend their partnership on LGWP MDI development services
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Orbia announces planned expansion of HFA 152a manufacturing capacity
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OzUK announces new GLP pilot plant for development of MDIs with LGWP propellants
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Honeywell announces agreement to supply HFO 1234ze for DevPro albuterol MDI, spin off of the advanced materials business
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Bespak and H&T Presspart launch new GMP pilot-scale MDI filling line for LGWP propellants
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AstraZeneca says that it has completed studies to support regulatory submissions for LGWP propellant version of Breztri (Trixeo) Aerosphere MDI
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Bespak announces that it will soon allocate capacity for new LGWP MDI filling line