Inhalation CDMO Vectura has announced an agreement to provide preclinical development services for Incannex Healthcare's IHL-216A CBD/isoflurane, which Incannex is developing for the treatment of traumatic brain injury. In addition to performing screening, stability, and optimization studies, Vectura will manufacture the IHL-216A needed for toxicology studies. Monash … [Read more...] about Incannex signs agreement with Vectura for preclinical development of its inhaled CBD/isoflurane for the treatment of TBI
Products and Services
Adherium appoints new CEO, submits 510(k) application for next generation Hailie sensor after rejecting takeover bid
Inhaler monitoring company Adherium has submitted a 510(k) application for a new Hailie sensor designed to work with the Symbicort MDI the company announced. The company recently rejected a takeover bid from another Australian asthma monitoring company called Respiri and then named a new CEO, its sixth chief executive since 2017, saying that it "must continue … [Read more...] about Adherium appoints new CEO, submits 510(k) application for next generation Hailie sensor after rejecting takeover bid
Noveome signs agreement for commercial use of SipNose intranasal device for delivery of ST266
Noveome Biotherapeutics has signed a commercial license agreement for the use of SipNose’s intranasal Cribriform Targeted Device (CT6) for delivery of its ST266 secretome for the treatment of ophthalmological and CNS conditions the companies said. Noveome has been working with SipNose since 2015 and used the device in a Phase 1 trial of ST266 for optic nerve disease … [Read more...] about Noveome signs agreement for commercial use of SipNose intranasal device for delivery of ST266
Inhalation Sciences gets approval for PreciseInhale trial
The Swedish Medical Product Agency (Läkemedelsverket) has approved an application from Inhalation Sciences (ISAB) for a clinical trial of its PreciseInhale aerosol generation system, the company said. ISAB expects to initiate the trial in June 2021 and to complete the study by the end of the year. Inhalation Sciences first announced its intentions to validate … [Read more...] about Inhalation Sciences gets approval for PreciseInhale trial
Vectura to be acquired by the Carlyle Group
A newly formed company called Murano Bidco, which is controlled by the Carlyle Group, has agreed to pay approximately £958 million to acquire inhalation CDMO Vectura, the companies have announced. According to the announcement, Bidco was formed specifically for the purpose of acquiring Vectura. Vectura Chairman Bruno Angelici commented, "Vectura has made strong … [Read more...] about Vectura to be acquired by the Carlyle Group
Inhalation Sciences forms new scientific advisory board
Aerosol research instrument company Inhalation Sciences (ISAB) has announced the formation of a new scientific advisory board, which will begin meeting on June 1, 2021 to discuss how the company's PreciseInhale laboratory aerosol dosing system can be used once it has been validated for clinical use. Members of the new scientific advisory board include Carsten Ehrhardt … [Read more...] about Inhalation Sciences forms new scientific advisory board
Kindeva partners with Loughborough on low-GWP MDI propellants
Kindeva Drug Delivery (formerly 3M Drug Delivery Systems) has signed a knowledge transfer partnership (KTP) with Loughborough University for the development of lower GWP MDI propellants, the company announced. Kindeva says that it "will leverage the KTP to understand the physics involved in pharmaceutical spray generation, using computational fluid dynamic (CFD) … [Read more...] about Kindeva partners with Loughborough on low-GWP MDI propellants
Iconovo announces deal with Respiratorius for development of DPI
Iconovo will develop a dry powder formulation and a DPI for Phase 1 studies for Swedish respiratory drug company Respiratorius AB on a fee for service basis in a deal worth up to SEK 3 million, the company said. The project, which involves development of Respiratorius's RES030-085 for the treatment of COPD and severe asthma, would lead to a license agreement if … [Read more...] about Iconovo announces deal with Respiratorius for development of DPI
Koura launches HFA-152a development services
MDI propellant maker Koura has announced the launch of HFA-152a development and filling services at the company's facilities in Chester, UK. Koura (formerly Mexichem) first announced the possibility of using 152a as a low global warming potential (GWP) propellant for metered dose inhalers in 2016. In December 2019, Chiesi announced that it planned to bring a … [Read more...] about Koura launches HFA-152a development services
Iconovo announces expansion of deal with Amneal on generic Symbicort and launch of pharma division
DPI developer Iconovo has announced that its development deal with Amneal for a generic version of Symbicort has been amended to add US and Chinese marketing rights for Amneal and Nordic region marketing rights for Iconovo. Acquisition of the Nordic marketing rights also marks the launch of a new division of Iconovo, Iconovo Pharma. The original deal included … [Read more...] about Iconovo announces expansion of deal with Amneal on generic Symbicort and launch of pharma division