According to early stage CDMO Bend Bioscience, the company is now part of Florida-based CDMO CoreRx thanks to an equity investment by NovaQuest Private Equity, which acquired CoreRx in 2021. Bend Bioscience, which launched in 2021, will offer particle engineering and manufacturing services for a range of dosage forms, including dry powders for inhalation. Bend … [Read more...] about CoreRx adds particle engineering capabilities with Bend Bioscience deal
Products and Services
Ab Initio Pharma now able to manufacture OINDPs for clinical trials
Australian OINDP specialist CDMO Ab Initio announced that the Therapeutic Goods administration of Australia (TGA) has granted the company a license to manufacture finished inhalation products and nasal sprays, in addition to other dosage forms. Ab Initio says that the license allows it to offer services including manufacturing of finished products for clinical trials, … [Read more...] about Ab Initio Pharma now able to manufacture OINDPs for clinical trials
Honeywell begins large-scale production of medical grade Solstice Air HFO-1234ze MDI propellant
Honeywell has begun large scale manufacturing of Solstice Air HFO-1234ze(E), a low global-warming-potential (GWP) MDI propellant, at a facility located in Baton Rouge, LA, USA, the company said. In February 2022, AstraZeneca announced that it would reformulate Breztri budesonide/ glycopyrronium/ formoterol fumarate using Solstice Air as part of a partnership … [Read more...] about Honeywell begins large-scale production of medical grade Solstice Air HFO-1234ze MDI propellant
HCmed Innovations and AeroRx Therapeutics partner on nebulized LABA/LAMA for COPD
Startup inhaled drug developer AeroRx Therapeutics and nebulizer maker HCmed Innovations have announced that they will partner on development of a nebulized LABA/LAMA inhalation solution for the treatment of COPD. AeroRx is a spinoff of iPharma Labs, which was acquired by Kindeva Drug Delivery earlier this year. In March 2022, HCmed announced that it was partnering … [Read more...] about HCmed Innovations and AeroRx Therapeutics partner on nebulized LABA/LAMA for COPD
Transpire Bio contracts with Recipharm for development of two more inhaled drugs
After announcing a deal with Recipharm for development of two inhaled drugs (TRB-1 and TRB-2) earlier this year, Transpire Bio says that it has signed an agreement with the CDMO for development of an additional two inhaled products. Under the new agreement, Recipharm will provide development services for Transpire's TRB-3 and TRB-4 inhaled therapeutics for the … [Read more...] about Transpire Bio contracts with Recipharm for development of two more inhaled drugs
Vectura gets go-ahead to build new facility for its Inhalation Centre of Excellence
According to inhalation CDMO Vectura, the company been granted planning permission to build a new £58 million, 10,000 sq m facility in Southwest England to house the company's Inhalation Centre of Excellence, with construction expected to be completed in 2025. The company said that it aims for the building on the Bristol & Bath Science Park to receive a BREEAM … [Read more...] about Vectura gets go-ahead to build new facility for its Inhalation Centre of Excellence
Nanopharm and Fluidda team up to help inhaled drug developers pursue the alternative bioequivalence pathway
OINDP development specialist Nanopharm, which was acquired by Aptar Pharma in 2019, and functional respiratory imaging (FRI) company Fluidda are teaming up to help sponsors of ANDAs for inhaled drugs for asthma and COPD avoid the need for clinical end-point studies by pursuing the alternative bioequivalence pathway. Sponsors of 505(b)(2) NDAs for inhaled drugs and … [Read more...] about Nanopharm and Fluidda team up to help inhaled drug developers pursue the alternative bioequivalence pathway
MedPharm to provide development services for Mosanna’s MOS-118 potassium channel blocker nasal spray for sleep apnea
CDMO MedPharm has announced that it will provide formulation and delivery development services for Swiss startup Mosanna Therapeutics' MOS-118 potassium channel blocker, with the goal of advancing a nasal spray formulation into clinical development for the treatment of metabolic obstructive sleep apnea (MOSA). Mosanna was formed recently to develop MOS-118 (formerly … [Read more...] about MedPharm to provide development services for Mosanna’s MOS-118 potassium channel blocker nasal spray for sleep apnea
H&T Presspart partners with OzUK on MDI development services
Device maker H&T Presspart has partnered with CRO OzUK in order to offer complete development services for metered dose inhalers to H&T Presspart customers. OzUK, which specializes in MDIs and other liquid-based OINDPs, will provide formulation and testing services in conjunction with delivery device development services offered out of H&T Presspart's … [Read more...] about H&T Presspart partners with OzUK on MDI development services
Copley Scientific launches EnviroMate environmental control chamber for OINDP testing
OINDP testing equipment maker Copley Scientific has announced the launch of the EnviroMate benchtop environmental control chamber, which is designed to reduce variability in OINDP testing that can occur due to inconsistent temperature, humidity, and electrostatic conditions. The chamber allows for DDU and APSD testing in a controlled environment without the need for a … [Read more...] about Copley Scientific launches EnviroMate environmental control chamber for OINDP testing