BlueWillow Biologics and Medigen Vaccine Biologics Corporation (MVC) have announced that a preclinical study of their BW-1019 intranasal COVID-19 booster demonstrated that giving the nasal vaccine after intramuscular vaccination induced neutralizing antibodies and protected against disease in a hamster model. According to the companies, no detectable virus was found … [Read more...] about Intranasal COVID-19 booster elicits mucosal immunity and protects against infection in preclinical studies
News
Positive Phase 1 results for HRT’s naloxone nasal spray
Non-profit pharma company Harm Reduction Therapeutics (HRT) said that a Phase 1 clinical trial of its HRT001 naloxone nasal spray in healthy volunteers met its primary endpoint, demonstrating the bioequivalence of a 3.0 mg dose of HRT001 to a 0.4 mg dose of intramuscular naloxone at 2.5 and 5 minutes post dose. Funding for the study came from OxyContin manufacturer … [Read more...] about Positive Phase 1 results for HRT’s naloxone nasal spray
Broughton launches US subsidiary
Broughton, a CRO that offers development and analysis of inhaled drugs, especially nicotine and cannabinoid products, has announced the establishment of a US subsidiary. Tony Jones, who has most recently been Senior Managing Health Scientist at consulting firm Cardno Chemrisk, was named Managing Consultant of the new business. Jones commented, "I am delighted to be … [Read more...] about Broughton launches US subsidiary
Pulmatrix hires Margaret Wasilewski as Chief Medical Officer
DPI developer Pulmatrix has hired Margaret Wasilewski as its Chief Medical Officer, the company said. Wasilewski most recently offered consulting services as President of ID Remedies, and her previous experience includes clinical development positions at Shire, Tetraphase Pharmaceuticals, Targanta Therapeutics, and Eli Lilly. Pulmatrix's pipeline includes … [Read more...] about Pulmatrix hires Margaret Wasilewski as Chief Medical Officer
TFF Pharmaceuticals partners with Catalent for DPI development and manufacturing
TFF Pharmaceuticals has partnered with CDMO Catalent for scale-up and manufacturing of dry powder formulations based on TFF's thin film freezing technology the companies have announced. The partnership will make the TFF technology available to other Catalent clients as well. Catalent notes that the TFF technology is its second addition to its inhaled dry powder … [Read more...] about TFF Pharmaceuticals partners with Catalent for DPI development and manufacturing
Thomas G. O’Riordan named Editor-in-Chief of the Journal of Aerosol Medicine and Pulmonary Drug Delivery
The Journal of Aerosol Medicine and Pulmonary Drug Delivery, the official journal of the International Society for Aerosols in Medicine (ISAM), has announced that GSK VP US Medical and Therapy Head for Respiratory Thomas G. O’Riordan will take over as Editor-in-Chief as of March 1, 2022. His predecessor, Gerry Smaldone, announced in October 2021 that he would step … [Read more...] about Thomas G. O’Riordan named Editor-in-Chief of the Journal of Aerosol Medicine and Pulmonary Drug Delivery
COPD Foundation partners with ENA Respiratory on development of pan-antiviral nasal spray
The COPD Foundation has partnered with ENA Respiratory for development of ENA's INNA-051 pegylated TLR2/6 agonist pan-antiviral nasal spray in patients with chronic lung disease, the company said. In June 2021, ENA Respiratory announced that it had raised A$32 million for development of INNA-051 and planned a Phase 1 trial. According to ENA, the Phase 1 study of … [Read more...] about COPD Foundation partners with ENA Respiratory on development of pan-antiviral nasal spray
Kindeva announces second lower-GWP MDI manufacturing line
CDMO Kindeva Drug Delivery has announced that it will invest in a second MDI manufacturing line capable of filling lower global warming potential (GWP) propellants such as HFA 152a and HFO 1234ze in response to increasing demand. The company announced plans to install its first lower-GWP propellant filling line in November 2021. The new line is expected to be … [Read more...] about Kindeva announces second lower-GWP MDI manufacturing line
Ferrer gets distribution rights to Tyvaso inhalation solution in much of the world
Ferrer has acquired the rights to distribute United Therapeutics' Tyvaso treprostinil inhalation solution for the treatment of pulmonary hypertension associated with interstitial lung disease (PH-ILD) outside of the US, Canada, Israel, Japan, and China. Terms of the deal were not disclosed. Tyvaso inhalation solution is currently approved for the treatment of … [Read more...] about Ferrer gets distribution rights to Tyvaso inhalation solution in much of the world
Gilbert Technologies names Scott Fleming Chief Commercial Officer
Gilbert Technologies, which is developing a soft mist inhaler device based on electrohydrodynamic atomization technology, announced that Scott Fleming will take on the role of Chief Commercial Officer. Fleming, who has been the company's Technology Director for the past two years, has extensive experience in OINDPs. A co-founder of inhaled drug developer Microdose … [Read more...] about Gilbert Technologies names Scott Fleming Chief Commercial Officer