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Medical

Positive results for Lightlake intranasal naloxone study

According to Lightlake Therapeutics, initial results from a two-week PK study of intranasal naloxone for the treatment of opioid overdose shows that the nasal spray gets naloxone into the bloodstream as fast as injection. The study, which began September 23, 2013, was conducted in conjunction with the National Institute on Drug Abuse (NIDA). Lightlake CFO Kevin … [Read more...] about Positive results for Lightlake intranasal naloxone study

Study finds out-of-hospital intranasal fentanyl safe and effective

A study by Danish researchers published online November 25, 2013 by the Annals of Emergency Medicine found that intranasal fentanyl administered by ambulance workers prior to delivery of patients to the hospital appeared to be safe and effective. The study involved over 900 patients, including adults and children older than 8, who were in severe pain. The patients … [Read more...] about Study finds out-of-hospital intranasal fentanyl safe and effective

Japanese launches for Flutiform, Ultibro

Two inhalation combination products have been launched in Japan within a day of each other. Skyepharma has announced that its Japanese partner Kyorin launched a 56-inhalation version of the Flutiform fluticasone/formoterol MDI, and Sosei has announced that Novartis Pharma KK launched Ultibro glycopyrronium/indacaterol inhalation capsules for the treatment of COPD. … [Read more...] about Japanese launches for Flutiform, Ultibro

Cornerstone launches Bethkis tobramycin inhalation solution

Cornerstone Therapeutics has launched Bethkis tobramycin inhalation solution for the treatment of cystic fibrosis patients with P. aeruginosa infections in the US, the company said. According to Cornerstone, one dose of Bethkis contains 300 mg of tobramycin in 4 mls of solution and can be delivered in about 15 minutes using a PARI LC Plus nebulizer. The company … [Read more...] about Cornerstone launches Bethkis tobramycin inhalation solution

Milestone initiates Phase 1 trial of intranasal calcium channel antagonist

Canadian cardiovascular drug development company Milestone Pharmaceuticals has initiated a Phase 1 clinical trial of its lead product, MSP-2017 intranasal short-acting calcium channel antagonist for the treatment of paroxysmal supraventricular tachycardia (PSVT), the company announced. The randomized, double-blind, placebo-controlled crossover study will take place in … [Read more...] about Milestone initiates Phase 1 trial of intranasal calcium channel antagonist

Puget Technologies says it will develop intranasal cannabinoids

Florida-based Puget Technologies has announced that its subsidiary Cannabis Biotech has initiated a research project to develop an intranasal formulation of cannabinoids, saying that the "project is targeted towards those who desire the benefits of medical marijuana but do not want the harmful effects or stigma of smoking it." The company said that the project will be … [Read more...] about Puget Technologies says it will develop intranasal cannabinoids

Insmed provides update on Arikace for NTM

Insmed has announced that it anticipates discussions with the EMA by the end of 2013 regarding Arikace inhaled liposomal amikacin for the treatment of nontuberculous mycobacterial (NTM) lung disease and that it has already initiated the Scientific Advice Working Party (SAWP) process. The company says that it is also looking to take advantage of a "globally … [Read more...] about Insmed provides update on Arikace for NTM

Nephron recalls albuterol inhalation solution

Nephron Pharmaceuticals has announced a voluntary recall of ten lots of albuterol inhalation solution "as a precautionary measure, due to results from . . . internal monitoring processes." The company says that it has not received reports of reportable adverse events for the 0.083% solution and that the lots met Nephron's quality specifications when … [Read more...] about Nephron recalls albuterol inhalation solution

Positive results in artificial pancreas plus inhaled insulin study

Diabetes research organization JDRF, along with Sansum Diabetes Research Institute, and the College of Engineering at University of California, Santa Barbara (UCSB) have announced positive results from a trial of an artificial pancreas used in conjunction with inhaled insulin taken at mealtimes. In 2010, MannKind Corporation announced that it would provide Afrezza … [Read more...] about Positive results in artificial pancreas plus inhaled insulin study

Avanir publishes data on intranasal sumatriptan

Avanir Pharmaceuticals has published results of a pharmacokinetic study of its AVP-825 intranasal sumatriptan powder for the treatment of acute migraine. Avanir licensed AVP-825 from OptiNose in July 2013, and the powder is delivered using the OptiNose breath-activated intranasal device. The study, published in Headache, compared AVP-825 to liquid nasal spray, oral … [Read more...] about Avanir publishes data on intranasal sumatriptan

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