Alpha Cognition announced that the Army Medical Research and Material Command has awarded the company a $750,000 grant to support a pre-clinical study of the possible use of ALPHA-1062 Intranasal galantamine for the treatment of blast-induced mild traumatic brain injury (mTBI). According to Alpha Cognition, the study will be conducted in partnership with the Seattle … [Read more...] about Alpha Cognition gets $750,000 grant from US military for development of ALPHA-1062 intranasal galantamine for the treatment of brain injury
Medical
Altamira says trial of Bentrio bentonite-based nasal spray for SAR met its primary endpoint
Altamira Therapeutics announced that the NASAR trial comparing its Bentrio bentonite-based gel nasal spray to saline nasal spray in patients with seasonal allergic rhinitis met its primary endpoint, demonstrating a statistically significant reduction in nasal allergy symptoms. The OTC nasal spray is currently available in Germany and has received 510(k) clearance in … [Read more...] about Altamira says trial of Bentrio bentonite-based nasal spray for SAR met its primary endpoint
Aerami says it will advance AER-901 inhaled imatinib into a Phase 2 trial for PAH and PH-ILD
Aerami Therapeutics said that pre-clinical and Phase 1 data presented recently at ATS support advancing the company's AER-901 nebulized imatinib into a Phase 2 trial that will include both patients with pulmonary arterial hypertension (PAH) and patients with pulmonary hypertension associated with interstitial lung disease (PH-ILD). The company said that it expects to … [Read more...] about Aerami says it will advance AER-901 inhaled imatinib into a Phase 2 trial for PAH and PH-ILD
Ceapro presents pre-clinical data from study of inhalable yeast beta glucan
Ceapro has presented results from a pre-clinical study of inhalable yeast beta glucans processed with the company's pressurized gas expanded (PGX) technology at ATS, the company said. The study, which was conducted in collaboration with McMaster University, evaluated the aerosolization characteristics of inhaled PGX-processed yeast beta glucans (PGX-YBG) and the … [Read more...] about Ceapro presents pre-clinical data from study of inhalable yeast beta glucan
Lumen Bioscience to develop antiviral intranasal powder for US Department of Defense
Lumen Bioscience said that it has received a contract worth $8.8 million from the Defense Innovation Unit (DIU) of the US Department of Defense for development of "a prototype broad-spectrum, fast-acting intranasal powder for treatment and prevention of known and emerging viral respiratory infections." The funding is part of "Project Panacea," run by DIU and the Joint … [Read more...] about Lumen Bioscience to develop antiviral intranasal powder for US Department of Defense
Codagenix initiates pediatric Phase 1 trial of CodaVax-RSV intranasal vaccine for the prevention of RSV
Codagenix announced that it has initiated a Phase 1 study of its CodaVax-RSV live-attenuated intranasal vaccine candidate in children aged 6 months to 5 years, with the study expected to enroll 18 children aged 2 to 5 years and 33 children aged less than 2 years. The FDA cleared an IND for the study in mid-2022. A previous Phase 1 study evaluated the nasal spray in … [Read more...] about Codagenix initiates pediatric Phase 1 trial of CodaVax-RSV intranasal vaccine for the prevention of RSV
Huro Biotech gets manufacturing rights for Destiny Pharma and SporeGen’s SPOR-COV bacillus nasal spray
Destiny Pharma and SporeGen have announced that Vietnamese biotechnology company Huro Biotech has acquired non-exclusive manufacturing rights for SPOR-COV bacillus nasal spray as well as exclusive marketing rights to the nasal spray in Vietnam. Huro has also launched an OTC nasal spray in Vietnam based on SPOR-COV technology, the companies said. In September 2020, … [Read more...] about Huro Biotech gets manufacturing rights for Destiny Pharma and SporeGen’s SPOR-COV bacillus nasal spray
Zambon announces completion of enrollment in Phase 3 studies of inhaled liposomal cyclosporine A for the treatment of BOS
Zambon has announced that the Phase 3 BOSTON-1 and BOSTON-2 trials of liposomal cyclosporine A for inhalation (L-CsA-i) have completed enrollment. The two trials were initiated by Breath Therapeutics in March 2019 prior to that company's acquisition by Zambon. Breath Therapeutics was spun off from PARI Pharma in 2017 to develop L‑CsA‑i, which has received Fast Track … [Read more...] about Zambon announces completion of enrollment in Phase 3 studies of inhaled liposomal cyclosporine A for the treatment of BOS
Arrowhead reports interim data from Phase 1/2a trial of ARO-RAGE inhaled RNAi for lung diseases
Arrowhead Pharmaceuticals said that interim data from the ARORAGE-1001 Phase 1/2a trial of its ARO-RAGE inhaled RNAi therapeutic, which it is developing for the treatment of inflammatory lung diseases, demonstrate reductions in soluble receptor for advanced glycation end products (RAGE) as high as 90% in healthy volunteers at the 4th highest dose with no indications … [Read more...] about Arrowhead reports interim data from Phase 1/2a trial of ARO-RAGE inhaled RNAi for lung diseases
Ritedose begins manufacturing 0.5% albuterol sulfate inhalation solution ampules
Ritedose Corporation, which says that it is the largest manufacturer of albuterol sulfate inhalation solution in the US, announced that it has begun compounding 5 mg/ml albuterol sulfate inhalation solution ampules through the 503B manufacturing process in response to a shortage, with shipping directly to hospitals expected to begin in May of this year. The … [Read more...] about Ritedose begins manufacturing 0.5% albuterol sulfate inhalation solution ampules