A new DPI designed for Sun Pharma by Cambridge Consultants has been on display at DDL 21. The inhaler is designed to work with carrier formulations and, according to the companies, reduces deposition in throat to such an extent that it can be loaded with approximatley half the API necessary for a traditional inhaler dose. The device also features a dose counter and a … [Read more...] about Cambridge Consultants and Sun launch new DPI at DDL
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Decision Resources predicts Spiriva will increase market share for COPD
According to a study by Decision Resources, primary care physicians prefer Boehringer Ingelheim's Spiriva to other first-line COPD treatments, with 44% surveyed saying they would increase their use of the drug in the next few years. That percentage is down from 59% in 2009. Read the company's press release. … [Read more...] about Decision Resources predicts Spiriva will increase market share for COPD
Insmed acquires Transave and its Arikace inhaled liposomal amikacin
Richmond, Virginia biopharmaceutical company Insmed Incorporated has announced a "business combination" with Transave, making Transave a wholly-owned subsidiary. The company also announced plans for Phase 3 trials of Arikace inhalation solution for the treatment of pseudomonas infections in CF patients and for the treatment of non-TB mycobacteria lung … [Read more...] about Insmed acquires Transave and its Arikace inhaled liposomal amikacin
Gates Foundation awards $6 million grant to NanoBio for intranasal RSV vaccine
University of Michigan spin-off NanoBio Corporation has received its second grant for vaccine development from the Bill and Melinda Gates Foundation. The new $6 million grant is for development of an intranasal vaccine for respiratory syncytial virus (RSV). No approved RSV vaccines are available currently. In 2005, prior to the spin off from UM, the company received … [Read more...] about Gates Foundation awards $6 million grant to NanoBio for intranasal RSV vaccine
GSK increases investment in Relovair development
GlaxoSmithKline has increased its share of Theravance, with which it is developing Relovair fluticasone/vilanterol COPD product, to approximately 19%. In addition, GSK is crediting a UK "patent box" proposal to encourage R&D investments with in announcing its final decision to invest in its facility in Ware, Hertfordshire for the manufacture of the new … [Read more...] about GSK increases investment in Relovair development
Mannkind announces positive Phase 3 results while facing clinical trial fraud accusations
Having recently announced that it stands by its clinical trials after a former executive filed suit against the company for retaliatory termination after he raised concerns about the validity of studies conducted in Russia and Bulgaria, Mannkind has released new data from a Phase 3 bioequivalence study of its Afrezza inhaled insulin. The new data concern the … [Read more...] about Mannkind announces positive Phase 3 results while facing clinical trial fraud accusations
Microdose and Nexus6 announce partnership
Microdose Therapeutx will now be able to offer the Nexus6 SmartinhalerLive technology as an integral component of its electronic dry powder inhaler. The Nexus6 technology will allow the Microdose DPI to provide real-time reporting of compliance and dosing data via wireless uploads. Read the company's press release. … [Read more...] about Microdose and Nexus6 announce partnership
Federal grant for THC nasal spray development
Summit Biosciences has received almost $150k in qualifying therapeutic discovery project (QTDP) grants for development of its synthetic THC nasal spray. According to Summit, it will use the money to hire new personnel for the development project. Read the company's press release. … [Read more...] about Federal grant for THC nasal spray development
Bitop initiates trial of Ectoin inhalation solution
German biotech company bitop AG announced that it has begun enrolling patients in a clinical trial of its Ectoin inhalation solution for the treatment of airway inflammation. In addition to the inhalation solution, bitop is also developing an Ectoin nasal spray and and a DPI. According to bitop, Ectoin is a naturally-occurring "cell protection … [Read more...] about Bitop initiates trial of Ectoin inhalation solution
Hovione wins patent case involving fluticasone intermediates
The United States Patent and Trademark Office has found that Hovione's method for making flumethasone and an analogue was not obvious, upholding the company's patent. A previous reexamination based on a 2005 claim had found that the method was obvious and that the patent should be canceled. An appeals board overturned that ruling after hearing oral arguments in … [Read more...] about Hovione wins patent case involving fluticasone intermediates