Business

Transpire Bio, which launched in 2022 to develop inhaled therapeutics for both local and systemic delivery, has officially opened its new headquarters and research facility in Weston, FL, USA. Shortly after launching, the company announced deals with Recipharm for development of 4 inhaled formulations (TRB-1, TRB-2, TRB-3, and TRB-4) and with INTO for 3 additional … [Read more...] about Transpire Bio opens new headquarters and research facility

According to MannKind Corporation, the United States Patent and Trademark Office (USPTO) has issued US patent No. 11,793,808 ("Compositions of Clofazimine, Combinations Comprising Them, Processes for Their Preparation, Uses and Methods Comprising Them"), which covers the company's MNKD-101 clofazimine inhalation suspension, until 2039. MannKind is developing MNKD-101 … [Read more...] about MannKind gets US patent covering clofazimine inhalation suspension

Qnovia (formerly Respira Technologies) has announced a partnership with researchers at the University of Virginia (UVA) for the development of two new antimicrobial peptides for delivery via the company's RespiRx vibrating mesh nebulizer technology. The new candidates will be called QN-05, which will be developed for the treatment of pneumonia, and QN-06, for the … [Read more...] about Qnovia partners with University of Virginia for development of inhaled antimicrobial peptides

Startup Akita Biosciences, newly launched by faculty members of Brigham & Women's Hospital to develop intranasal therapies, has announced the availability of its first nasal product. The company says that Profi prophylactic nasal spray is "a drug-free formulation composed predominantly of ingredients that have previously been used intranasally at doses higher than … [Read more...] about Akita Biosciences launches Profi antiviral nasal spray

Oragenics will acquire Odyssey Health's breath-powered intranasal delivery device and dry powder nasal formulations, in a deal that includes 8 million shares of Oragenics Series F preferred stock and a total of $1 million in cash, the companies said. The drugs included in the deal are Odyssey's OPN-002 for the treatment of mild traumatic brain injury and ONP-001 for … [Read more...] about Oragenics to acquire Odyssey Health’s nasal delivery technology

Avalyn Pharma announced that an oversubscribed Series C financing brought in $175 million that the company will use for continued development of AP01 inhaled pirfenidone and AP02 inhaled nintedanib for the treatment of pulmonary fibrosis. Earlier this year, the company reported data from a Phase 1b trial of nebulized AP01 in patients with idiopathic pulmonary fibrosis … [Read more...] about Avalyn Pharma raises $175 million for continued development of AP01 inhaled pirfenidone and AP02 inhaled nintedanib

ReCode Therapeutics announced that it has raised $50 million as an extension to a Series B financing, with funds going toward clinical development of its inhaled mRNA therapies for the treatment of primary ciliary dyskinesia and cystic fibrosis. The company says that it has now raised a total of $260 million in Series B funding. ReCode CEO Shehnaaz Suliman … [Read more...] about ReCode Therapeutics announces additional funding for development of its inhaled mRNA therapies

The Western Australian Future Health Research and Innovation Fund has awarded a A$499,241 Innovation Seed Fund grant to Virex Pharma for development of Glyxine, an inhaled antiviral nanoemulsion, for the treatment of respiratory syncytial virus. According to Virex, the grant will go toward testing of Glyxine in epithelial cells and in animal models of RSV at Wal-yan … [Read more...] about Virex gets almost A$500,000 grant for development of GlyXine inhaled antiviral