Silo Pharma announced that it has signed a license agreement with Medspray Pharma for the use of Medspray’s soft mist spray technology for delivery of Silo’s SPC-15 intranasal ketamine. According to Silo, the Medspray technology delivers “A formulation-specific, customized aerosol plume that is designed to allow for better deposition in the relevant region of the nasal cavity, thereby reducing levels of systemic absorption. The drug dispersion through the nose to brain has been designed to optimize patient safety and therapeutic delivery.”
Columbia University is currently working with Silo to conduct preclinical studies of SPC-15, which Silo is developing for the treatment of stress disorders such as anxiety and PTSD. The company says that it plans to pursue the 505(b)(2) pathway for regulatory approval if clinical development is successful.
Silo Pharma CEO Eric Weisblum commented, “We began a collaboration with Medspray earlier this year for feasibility studies evaluating its patented technology as a delivery mechanism for our intranasal therapeutic drug SPC-15. Based on successful outcomes from these studies, we have selected Medspray’s spray technology for our formulation. As part of our manufacturing and sales contract, we have obtained exclusive rights to its spray mist technology for use with multiple indications including post-traumatic stress disorder (PTSD) and anxiety, as well as Alzheimer’s disease and anorexia. We believe these rights are a valuable asset that can support Silo’s continuing research and development of novel therapeutics.”
Read the Silo Pharma press release.
