Copley Scientific, which recently made multiple updates to its range of OINDP testing equipment, has announced the launch of a new range of accessories for testing nasal sprays, including metered dose and dry powder nasal products. The new Copley products include accessories for delivered dose uniformity (DDU) testing of nasal products as well as for improved in vitro-in vivo correlations in aerodynamic particle size distribution (APSD) testing of nasal products.
According to the company, the new Nasal Spray Dose Collector (NSDC) and Nasal Spray Waste Collector (NSWC) can be used for manual test methods or in conjunction with the company’s Vertus II/Plus automated shake and fire system to improve reproducibility of DDU testing.
The new Alberta Idealised Nasal Inlet (AINI), like the Alberta Idealised Throat and Child Alberta Idealised Throat, was developed by University of Alberta professor Warren Finlay. According to Copley, the aluminum inlet “is made up of four individual regions – the vestibule, turbinate, olfactory and nasopharynx – and mimics deposition behavior in each while simultaneously generating a sample that accurately reflects the respirable dose.”
The company adds that accessories also allow the Vertus II/Plus to interface with widely-used types of cascade impactors for APSD testing to evaluate nasal versus lung deposition, saying that “use of the Vertus II/Plus with cascade impactors such as the Next Generation Impactor and Andersen Cascade Impactor for this application, reduces measurement variability, boosts productivity, and alleviates health and safety concerns.”
Read the Copley Scientific press release.
