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Highlights from RDD 2018

Posters on the Podium
The authors of 8 posters selected to present their work during the Posters on the Podium session represented a cross-section of topics covered during the meeting. The 10-minute presentations included:

  • Jan Olof Svensson, AstraZeneca, “Fully Automated Delivered Dose Uniformity and Fine Particle Dose Testing of Dry Powder Inhalers: Analytical Principles Using UPLC with UV- and MS-detection”
  • Michaela Hänsel, Boehringer Ingelheim, “A Comparison of Product Carbon Footprints of Respimat® Versus Pressurized Metered Dose Inhalers” (presented by Joachim Eicher)
  • Sandra Grau-Bartual, Auckland University of Technology, “Effect of Positive Airway Pressure on Human Nasal And Bronchial Epithelial Cells.
  • Benjamin Spence, Virginia Commonwealth University, “Optimization of a Combination Device for High Efficiency Aerosol Delivery and High Flow Nasal Cannula Therapy”
  • Judith Heidland, Christian Albrecht University of Kiel, “Nano-in-microparticles for Dry Powder Vaccination: Nasal Application and Uptake in Immune Competent Cells
  • James Ivey, University of Alberta, “Isokinetic In-line Sampling Enables Rapid Characterization of Atomizers and Cyclones for Spray Drying Process Development”
  • Kian Min Lim, PA Consulting, “Robust Characterization of Inhalation Information Using a Deep Neural Network and Smartphone”
  • Mary Devlin Capizzi, Drinker Biddle and Reath, “The Future is Suddenly Here: Legal and Regulatory Considerations for Digital Health Apps and Inhalers”

Smart inhaler technology
In her poster presentation, Capizzi noted that the recent trend toward “smart” inhalers, which has generated a great deal of activity in the past few years, is evolving very quickly. RDD 2018 reflected some those rapid advances, including a supplier seminar focused on digital devices by 3M Drug Delivery Systems, “The 3M Intelligent Control Inhaler Platform and the Challenges of Incorporating Existing Molecules into Pressurized Metered Dose Inhalers (pMDIs)”; talks by David Van Sickle of Propeller Health, Paul Colthorpe of Novartis, Richard Costello of the Royal College of Surgeons, and John Blakey of Royal Liverpool Hospital on the impact of digital technology for patients and clinicians; and a number of connected devices on display in the exhibition.

Capizzi emphasized that the law has not yet caught up with this evolution but that enforcement will increase in the future. Blakey also sounded a note of caution, pointing out that the data burden imposed by digital technology, that “clinicians are a major obstacle,” and that studies have shown that patients may resist monitoring technology because “people don’t really like being spied upon.”

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published on May 4, 2018

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